---
product_id: 23133826
title: "Vetoquinol Zylkene Calming Support Supplement for Medium Dogs 33-65lbs Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs, 225mg"
brand: "vetoquinol"
price: "₨1768"
currency: SCR
in_stock: true
reviews_count: 8
category: "Vetoquinol"
url: https://www.desertcart.sc/products/23133826-vetoquinol-zylkene-calming-support-supplement-for-medium-dogs-33-65lbs
store_origin: SC
region: Seychelles
---

# Lactose-free & natural 225mg active calming dose Alpha-Casozepine milk protein Vetoquinol Zylkene Calming Support Supplement for Medium Dogs 33-65lbs Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs, 225mg

**Brand:** vetoquinol
**Price:** ₨1768
**Availability:** ✅ In Stock

## Summary

> 🐾 Calm, Confident, Connected — Because Your Dog Deserves the Best Chill

## Quick Answers

- **What is this?** Vetoquinol Zylkene Calming Support Supplement for Medium Dogs 33-65lbs Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs, 225mg by vetoquinol
- **How much does it cost?** ₨1768 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.sc](https://www.desertcart.sc/products/23133826-vetoquinol-zylkene-calming-support-supplement-for-medium-dogs-33-65lbs)

## Best For

- vetoquinol enthusiasts

## Why This Product

- Trusted vetoquinol brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Easy Food-Topper Capsule:** Simply open and sprinkle on food for hassle-free daily behavioral support
- • **Vet-Backed Calming Power:** Clinically proven 225mg dose to ease medium dog anxiety without sedation
- • **Natural Milk Protein Magic:** Alpha-Casozepine promotes relaxation without drowsiness or side effects
- • **Gentle on Sensitive Stomachs:** Lactose-free formula ensures daily calm without digestive upset
- • **Stress-Proof Your Dog’s Day:** Supports coping with travel, vet visits, loud noises & separation anxiety

## Overview

Vetoquinol Zylkene is a veterinarian-recommended calming supplement designed for medium dogs (33-65 lbs). Featuring 225mg of Alpha-Casozepine, a natural milk protein, it promotes relaxation and reduces anxiety without sedation or digestive issues. Easy to administer by adding to food, it helps dogs manage stress from travel, vet visits, loud noises, and separation, supporting daily behavioral balance and improved quality of life.

## Description

desertcart.com : Vetoquinol Zylkene Calming Support Supplement for Medium Dogs 33-65lbs Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs, 225mg : Pet Supplies

Review: Don’t hesitate! - Seriously buy this. Our pug has evening anxiety ever since the 4th of July. The vet prescribed Trazodone which made it so much worse and then she gave her Gabapentin which knocked her out and we don’t want to sedate her. The vet suggested to give this product a try and I can’t even believe how well it works, I would assume it was a script if I hadn’t known. We give it to her around 3:30 and by 5 she’s calm and chill, she is a little sleepy but more relaxed. It does not last all day. She is more like her normal self around 9:30 which is great bc it’s bedtime.
Review: Miracle in a Pill - Okay, this is going to sound like it was written by a relative, but I'm just your normal, average animal freak with five resident dogs and seven cats (two are fosters). Over the years we've had probably a hundred or more animals in our home, and we tend to adopt the misfits. Mango, our overanxious, neurotic rat terrier is one of our bigger challenges. She has to modes: catatonic and, as my friend put it, "tiny psycho dog." Over the years, we've done any number of behavioral, homeopathic, and medical interventions with only modest success. After a series of very volatile outbursts, our vet put her on a strong antianxiety medication before. We were thinking we may need to prepare ourselves for euthanasia, something we aren't in a rush to do, but after three years and thousands of dollars, we were running low on options. The drugs worked, but she was so zonked out there were nights we had to literally carry her upstairs. We knew we had to wean her off of the drugs but we were apprehensive about her reverting back to her old ways. The vet said one of the other vets had good luck with Zylkene, and said while it's spendy, maybe it was worth a shot. Since she's been completely off the drugs and exclusively on the Zylkene (about 3 months), she's gone from several occurrences of attacking the other animals (and occasionally is) a DAY to maybe twice in the past three months, and very easy to redirect to preferred behavior. I truly believe this stuff has saved the life of the dog who stole my heart. She's a confident and affectionate little girl who not only doesn't fight with her siblings, but actually cuddles with them! Remarkable! I haven't had the same luck with our other anxious dogs, but if say it's worth a shot of you're at wit's end.

## Features

- Help Your Pet Cope With External Stress - Zylkene helps your pet cope with changes in their daily routine, such as travel, celebrations, vet visits, home alone, boarding, loud noises, and more
- Alpha-Casozephine - A naturally occurring milk protein found in cow's milk that helps promote calming effects in your pet without drowsiness or other side effects found in other calming chews for dogs
- Lactose-Free and Easy on Sensitive Stomachs - Zylkene's dog calming and cat calming supplements are lactose-free and made with natural ingredients that are easy on sensitive stomachs
- Veterinarian Recommended Daily Calming Support - Zylkene promotes calming in dogs and cats and can be given daily for behavior support and to help deal with unexpected external stresses
- Easy to Administer - Open the capsule of Zylkene and add it to your pet's food daily to help them cope with external stresses like separation and improve daily behavior

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Active Ingredients | Dried hydrolyzed casein, maltodextrin, magnesium stearate |
| Brand | Vetoquinol |
| Customer Reviews | 4.0 out of 5 stars 1,532 Reviews |
| Flavor | Flavorless |
| Item Form | Capsule |
| Item Volume | 1 |
| Item Weight | 0.1 Grams |

## Product Details

- **Active Ingredients:** Dried hydrolyzed casein, maltodextrin, magnesium stearate
- **Brand:** Vetoquinol
- **Flavor:** Flavorless
- **Item Form:** Capsule
- **Item Weight:** 0.1 Grams

## Images

![Vetoquinol Zylkene Calming Support Supplement for Medium Dogs 33-65lbs Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs, 225mg - Image 1](https://m.media-amazon.com/images/I/719-u0swQoL.jpg)
![Vetoquinol Zylkene Calming Support Supplement for Medium Dogs 33-65lbs Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs, 225mg - Image 2](https://m.media-amazon.com/images/I/71CI21VlQdL.jpg)
![Vetoquinol Zylkene Calming Support Supplement for Medium Dogs 33-65lbs Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs, 225mg - Image 3](https://m.media-amazon.com/images/I/814W06PxkfL.jpg)
![Vetoquinol Zylkene Calming Support Supplement for Medium Dogs 33-65lbs Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs, 225mg - Image 4](https://m.media-amazon.com/images/I/817pU6y7K9L.jpg)
![Vetoquinol Zylkene Calming Support Supplement for Medium Dogs 33-65lbs Helps Promote Relaxation and Reduce External Stress Factors, Daily Behavioral Support and Anxiety Relief for Dogs, 225mg - Image 5](https://m.media-amazon.com/images/I/81HLgC0GohL.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Don’t hesitate!
*by L***N on August 3, 2025*

Seriously buy this. Our pug has evening anxiety ever since the 4th of July. The vet prescribed Trazodone which made it so much worse and then she gave her Gabapentin which knocked her out and we don’t want to sedate her. The vet suggested to give this product a try and I can’t even believe how well it works, I would assume it was a script if I hadn’t known. We give it to her around 3:30 and by 5 she’s calm and chill, she is a little sleepy but more relaxed. It does not last all day. She is more like her normal self around 9:30 which is great bc it’s bedtime.

### ⭐⭐⭐⭐⭐ Miracle in a Pill
*by J***H on June 7, 2016*

Okay, this is going to sound like it was written by a relative, but I'm just your normal, average animal freak with five resident dogs and seven cats (two are fosters). Over the years we've had probably a hundred or more animals in our home, and we tend to adopt the misfits. Mango, our overanxious, neurotic rat terrier is one of our bigger challenges. She has to modes: catatonic and, as my friend put it, "tiny psycho dog." Over the years, we've done any number of behavioral, homeopathic, and medical interventions with only modest success. After a series of very volatile outbursts, our vet put her on a strong antianxiety medication before. We were thinking we may need to prepare ourselves for euthanasia, something we aren't in a rush to do, but after three years and thousands of dollars, we were running low on options. The drugs worked, but she was so zonked out there were nights we had to literally carry her upstairs. We knew we had to wean her off of the drugs but we were apprehensive about her reverting back to her old ways. The vet said one of the other vets had good luck with Zylkene, and said while it's spendy, maybe it was worth a shot. Since she's been completely off the drugs and exclusively on the Zylkene (about 3 months), she's gone from several occurrences of attacking the other animals (and occasionally is) a DAY to maybe twice in the past three months, and very easy to redirect to preferred behavior. I truly believe this stuff has saved the life of the dog who stole my heart. She's a confident and affectionate little girl who not only doesn't fight with her siblings, but actually cuddles with them! Remarkable! I haven't had the same luck with our other anxious dogs, but if say it's worth a shot of you're at wit's end.

### ⭐⭐⭐⭐⭐ Not a total cure, but defiantly part of the stress relief plan
*by D***5 on April 16, 2016*

Some people may not find this to work, but for us, our 5 yr old puggle who has issues with fireworks and storms it helps a lot. It definitely works better then the doggie meds from the vet that just make it worse. We use this product along with the Thunder Shirt and we can really see a difference, of course its not going to make your pets issues just go away, its a very light sedative that for our dog takes the (edge off), when we think Buster needs it, like 4th of July, New years eve and approaching storms, we simply give him the recommend dose, and within about 20 min he started to feel a little better and within an hr he's able to go to his (safe place) and sleep. When dealing with dogs with issues, you really need to give them a SAFE place, somewhere they can go if they want and deal with they're stress. sometimes its on your lap and sometimes its in a bathroom or cage, but give them an option along with the Zylkene. Also, we play music at higher volumes for him, classical music is great. All in all, if your pet has stress issues, nothing is going to (fix) the issue easy. But there are things you can do to help and for us it the following: Zylkene Thunder Shirt Safe Place Classical music at levels not too loud but loud enough to blend in with fireworks or thunder. UPDATE~~We do use this but also some stronger prescription meds from our vet for when something stronger is needed, we happy to see a new FDA approved drug just released SILEO, so if your needing something stronger check into this.

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*Product available on Desertcart Seychelles*
*Store origin: SC*
*Last updated: 2026-01-23*