---
product_id: 3649743
title: "Advanced Digestive Enzymes - Supplement with Pepsin, Ox Bile & Pancreatin for Indigestion & Constipation Relief - Minimizes Occasional Gas & Bloating* - Third-Party Certified - 180 Capsules"
brand: "thorne"
price: "₨1923"
currency: SCR
in_stock: true
reviews_count: 13
category: "Thorne"
url: https://www.desertcart.sc/products/3649743-advanced-digestive-enzymes-supplement-with-pepsin-ox-bile-and-pancreatin
store_origin: SC
region: Seychelles
---

# 180 vegetarian capsules per bottle 4 rounds of purity & potency testing 3 key enzymes: Pepsin, Pancreatin & Ox Bile Advanced Digestive Enzymes - Supplement with Pepsin, Ox Bile & Pancreatin for Indigestion & Constipation Relief - Minimizes Occasional Gas & Bloating* - Third-Party Certified - 180 Capsules

**Brand:** thorne
**Price:** ₨1923
**Availability:** ✅ In Stock

## Summary

> 💥 Unlock your gut’s full potential — because thriving starts from within!

## Quick Answers

- **What is this?** Advanced Digestive Enzymes - Supplement with Pepsin, Ox Bile & Pancreatin for Indigestion & Constipation Relief - Minimizes Occasional Gas & Bloating* - Third-Party Certified - 180 Capsules by thorne
- **How much does it cost?** ₨1923 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.sc](https://www.desertcart.sc/products/3649743-advanced-digestive-enzymes-supplement-with-pepsin-ox-bile-and-pancreatin)

## Best For

- thorne enthusiasts

## Why This Product

- Trusted thorne brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Clean & Allergen-Free Formula:** Dairy, gluten, soy, nuts & shellfish free—perfect for sensitive, health-conscious professionals.
- • **Optimized for Modern Lifestyles:** Formulated to ease discomfort from rich meals, food sensitivities, and gallbladder removal.
- • **Sustained Energy & Wellness Boost:** Supports nutrient uptake that can enhance energy, reduce cravings, and promote natural weight balance.
- • **Precision-Crafted Digestive Support:** Advanced enzyme blend targets indigestion, gas & bloating for seamless nutrient absorption.
- • **Clinically Trusted & Third-Party Certified:** Backed by rigorous 4-step lab testing and preferred by 100+ pro sports teams.

## Overview

THORNE Advanced Digestive Enzymes is a premium, third-party tested supplement featuring a potent blend of pepsin, pancreatin, and ox bile designed to relieve occasional indigestion, gas, and bloating. With 180 vegetarian capsules per bottle, it supports nutrient absorption especially after heavy or challenging meals, trusted by healthcare practitioners and elite athletes alike.

## Description

Buy THORNE - Advanced Digestive Enzymes - Supplement with Pepsin, Ox Bile & Pancreatin for Indigestion & Constipation Relief - Minimizes Occasional Gas & Bloating* - Third-Party Certified - 180 Capsules on desertcart.com ✓ FREE SHIPPING on qualified orders

Review: Game-Changer... - It's rare that I write reviews anymore...but as I was standing at my sink doing dishes at 10 PM--without feeling completely exhausted--I had to stop what I was doing and write a review for this amazing product. I was just looking for a way to tolerate foods and avoid "issues" since I have developed a number of food allergies over the years. I was out of my go-to, and they no longer made it, so I was on the search for something that was as close to equal as possible. I WAS NOT EXPECTING EVERYTHING TO CHANGE. You guys!! Now, not only do I tolerate almost everything I'm allergic to, I have ENERGY, like, I must not have been absorbing ANY nutrients, because every day for me I felt like I was walking on loose sand...you know, the kind you trudge through with your hands full after leaving the beach with your stuff? And you feel like you're barely moving? Not the easy, mostly flat, wet sand. That was my all day every day for nearly 12 years. I NO LONGER FEEL LIKE THAT. I HAVE ENERGY TO WORK OUT. I AM NOT HUNGRY ALL THE TIME (I'm assuming I was extra hungry because though obese (due to no energy from not absorbing nutrients from my food), my body was STARVING. I have been walking almost double the amount of steps per day since I started. Sometimes more. Since I'm absorbing nutrients, I also noticed I'm not eating as much, and I have lost approximately 10 lbs. in the past two months. Y'all, this isn't a weight loss thing, but boy, when your body isn't starving from inability to absorb nutrients, it is AMAZING how much easier it is to put down the fork and have the extra energy to MOVE. SO, I can't say this is how it will be for everyone, but I just had to say thank you to the people at Thorne...you guys, between the Omega3-COQ10 and these Enzymes, I feel like I'm getting my life back. This was NOT what I expected when I took a chance with it. Thank you. One little con: for everyone new to this product, it takes a little trial and error for what your body can tolerate. The first few days I took it as directed and began to feel like there was a lump growing in my throat. I realized it could be causing acid reflux (like I didn't need quite that much dosing-wise). So I tapered and then when I knew I was going to be eating something I knew my body struggled with, I would take 2. If not, I would only take 1 or forego it altogether, again depending on what it was. As a result, that lump feeling/reflux went away, and it has been working perfectly ever since. But that is just my personal experience, not a direction for how to use it. Of course, as the bottle says, work with your doctor...I am NOT one. But as I am between doctors and I couldn't wait around for a suggestion since I was out of my old digestive enzymes, I stumbled on this, and I am ever so grateful I did.
Review: Excellent product! - After trying many different brands and products, this is the one that works best for me. I have been using other brands that are more economical but I have no real improvement ,and motivated me to start searching for new brands until I have found this one Thorne ADE which has improved my condition in a noticeable manner. Each person metabolism is different though ,results may vary depending upon each individual. I am using it and I am pretty happy with the results!

## Features

- Support for Indigestion: Benefits individuals who have occasional indigestion or food sensitivities, had gallbladder removal, or who have overused antacids*
- Comprehensive Formula: A blend of hydrochloric acid (HCl) , pepsin, pancreatin, and ox bile to promote the digestion and absorption of essential nutrients from the food we eat*
- Promotes Digestion: Can help ease digestive discomfort that may occur after a meal heavy in fat or red meat, when enjoying foods that cause extra gas and bloating, or when partaking in an occasional overindulgence*
- 4 Rounds of Testing: Our state-of-the-art laboratories enable us to conduct 4 rounds of testing on every product, from analyzing the purity of raw materials to confirming the shelf life of finished formulas
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B000VYQJ8W |
| ASIN  | B000VYQJ8W |
| Age Range Description | Adult |
| Allergen Information | Dairy Free, Egg Free, Fish Free, Gluten Free, Peanut Free, Shellfish Free, Soy Free, Tree Nut Free |
| Best Sellers Rank | #8,482 in Health & Household ( See Top 100 in Health & Household ) #21 in Multi-Enzyme Nutritional Supplements |
| Brand Name | THORNE |
| Container Type | Bottle |
| Customer Reviews | 4.6 4.6 out of 5 stars (1,497) |
| Date First Available  | September 13, 2007 |
| Dosage Form | Capsule |
| Flavor | Gallbladder |
| Global Trade Identification Number | 00693749405023 |
| Is Discontinued By Manufacturer  | No |
| Item Dimensions | 2.89 x 2.89 x 5.22 inches |
| Item Form | Capsule |
| Item model number  | 6.93749E+11 |
| Manufacturer | Thorne Research |
| Manufacturer  | Thorne Research |
| Manufacturer Part Number | SD405 |
| Material Features | Vegetarian |
| Model Number | 6.93749E+11 |
| Number of Items | 1 |
| Primary Supplement Type | Magnesium |
| Product Benefits | Gut Health Support |
| Product Dimensions  | 2.89 x 2.89 x 5.22 inches; 6.56 ounces |
| Total Servings Per Container | 90 |
| UPC | 693749405023 |
| Unit Count | 180.00 Count |

## Product Details

- **Age Range (Description):** Adult
- **Brand:** THORNE
- **Flavor:** Gallbladder
- **Item Form:** Capsule
- **Item dimensions L x W x H:** 2.89 x 2.89 x 5.22 inches
- **Number of Items:** 1
- **Package Information:** Bottle
- **Primary Supplement Type:** Magnesium
- **Product Benefits:** Gut Health Support
- **Unit Count:** 180.00 Count

## Images

![Advanced Digestive Enzymes - Supplement with Pepsin, Ox Bile & Pancreatin for Indigestion & Constipation Relief - Minimizes Occasional Gas & Bloating* - Third-Party Certified - 180 Capsules - Image 1](https://m.media-amazon.com/images/I/71T57VDofpL.jpg)

## Available Options

This product comes in different **Size** options.

## Questions & Answers

**Q: Has anyone here used and compared and Thorne Bio-Gest against Thorne Betaine HCL & Pepsin?  Which worked better for you (and for what issue)?  Thanks!**
A: The only difference between the two is the BIO-GEST uses ox-bile. Which is used to assist in digestion of lipids. The liver and the gallbladder both make bile salts to digest fats. If you are having problems with your liver or have had your gallbladder removed take the BIO-GEST. Even if you don't think you have any problems in that department taking the BIO-GEST is still the recommended choice.

**Q: What is the benefit of  l-glutamic acid hcl as opposed to all betaine hcl?**
A: The Bio-Gest is based on an old time formula that included both. Both the glutamic acid and the betaine are carrier molecules for the HCl. The difference is glutamic acid converts to glutamine to support a healthy GI lining. The betaine helps with liver detox.

**Q: I just opened a brand new bottle and there is a very strong smell...is that normal? It smells very foul. This is my first time with this product.**
A: Just stuck my nose in our almost-empty bottle and, yes, pungent smell.  I don't think it means anything more than some loose dust in the bottle from the production process.  They can use cool blowers on sealed capsules, but most powdered supplements have some residual. (As someone else noted.)  I think it's most likely fine.  It's possible one capsule is broken, and you can dump them out carefully to inspect, but I probably wouldn't bother.  Just take them because they help greatly -- best effect for us is taking 15 minutes after meal. (Set a timer so you don't forget!)  I read advice from someone in Facebook group for low FODMAP diet (where I learned about these, as my doctor offered no such helpful suggestions) that their nutritionist recommended taking not just two, but three capsules per meal for maximum benefit.  We tried that, after finding that two worked very well but, with certain foods, upping to 3 per meal was even better.  (My husband also takes with Source Naturals Essential Enzymes Ultra.  But he has no gall bladder and 1/3 less intestines so he really needs the extra enzymes, esp to break down fats and fiber.)  Try them a week, but also keep a food journal and see if you can identify trigger foods.  (Stress also wreaks havoc with digestion, so avoid that as best you can.  If you can't, modify how you respond to stressors and try some chilling out exercises like yoga, meditation, or mindful breathing.  It's effective if even you don't believe.)  Good luck.  Check back and tell us how it worked for you.

**Q: Does this have any probiotics in it?**
A: Thorne's Bio-Gest does not contain digestive enzymes. Thorne does have a suite of probiotic supplement products, but Bio-Gest is not one of them.

## Customer Reviews

### ⭐⭐⭐⭐⭐ Game-Changer...
*by A***T on June 28, 2024*

It's rare that I write reviews anymore...but as I was standing at my sink doing dishes at 10 PM--without feeling completely exhausted--I had to stop what I was doing and write a review for this amazing product. I was just looking for a way to tolerate foods and avoid "issues" since I have developed a number of food allergies over the years. I was out of my go-to, and they no longer made it, so I was on the search for something that was as close to equal as possible. I WAS NOT EXPECTING EVERYTHING TO CHANGE. You guys!! Now, not only do I tolerate almost everything I'm allergic to, I have ENERGY, like, I must not have been absorbing ANY nutrients, because every day for me I felt like I was walking on loose sand...you know, the kind you trudge through with your hands full after leaving the beach with your stuff? And you feel like you're barely moving? Not the easy, mostly flat, wet sand. That was my all day every day for nearly 12 years. I NO LONGER FEEL LIKE THAT. I HAVE ENERGY TO WORK OUT. I AM NOT HUNGRY ALL THE TIME (I'm assuming I was extra hungry because though obese (due to no energy from not absorbing nutrients from my food), my body was STARVING. I have been walking almost double the amount of steps per day since I started. Sometimes more. Since I'm absorbing nutrients, I also noticed I'm not eating as much, and I have lost approximately 10 lbs. in the past two months. Y'all, this isn't a weight loss thing, but boy, when your body isn't starving from inability to absorb nutrients, it is AMAZING how much easier it is to put down the fork and have the extra energy to MOVE. SO, I can't say this is how it will be for everyone, but I just had to say thank you to the people at Thorne...you guys, between the Omega3-COQ10 and these Enzymes, I feel like I'm getting my life back. This was NOT what I expected when I took a chance with it. Thank you. One little con: for everyone new to this product, it takes a little trial and error for what your body can tolerate. The first few days I took it as directed and began to feel like there was a lump growing in my throat. I realized it could be causing acid reflux (like I didn't need quite that much dosing-wise). So I tapered and then when I knew I was going to be eating something I knew my body struggled with, I would take 2. If not, I would only take 1 or forego it altogether, again depending on what it was. As a result, that lump feeling/reflux went away, and it has been working perfectly ever since. But that is just my personal experience, not a direction for how to use it. Of course, as the bottle says, work with your doctor...I am NOT one. But as I am between doctors and I couldn't wait around for a suggestion since I was out of my old digestive enzymes, I stumbled on this, and I am ever so grateful I did.

### ⭐⭐⭐⭐⭐ Excellent product!
*by F***A on March 27, 2026*

After trying many different brands and products, this is the one that works best for me. I have been using other brands that are more economical but I have no real improvement ,and motivated me to start searching for new brands until I have found this one Thorne ADE which has improved my condition in a noticeable manner. Each person metabolism is different though ,results may vary depending upon each individual. I am using it and I am pretty happy with the results!

### ⭐⭐⭐⭐⭐ Great product!
*by M***O on April 9, 2026*

This product has helped me with my stomach issues tremendously! My nutritionist recommended it to me and I’m so glad to have listened!

## Frequently Bought Together

- THORNE Advanced Digestive Enzymes (Formerly Bio-Gest) - Blend of Digestive Enzymes to Aid Digestion* - Gut Health Support with Pepsin, Ox Bile, Pancreatin - 180 Capsules - 90 Servings
- THORNE Basic Nutrients 2/Day - Comprehensive Daily Multivitamin with Optimal Bioavailability - Vitamin & Mineral Formula - Gluten, Dairy & Soy-Free - 60 Capsules - 30 Servings
- THORNE Berberine - Dual Action Formula with Phytosome Plus Botanical Extract - Support Heart Health, Immune System, Healthy GI, Cholesterol* - Gluten-Free, Dairy-Free - 60 Capsules - 30 Servings

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---

*Product available on Desertcart Seychelles*
*Store origin: SC*
*Last updated: 2026-04-23*