Question 1

If 50% of regular ALA is useless then wouldn't a 600mg pill of regular ALA still have 300mg of effective ALA vs the 100mg is this version?

Accepted Answer

When you have s-LA competing to the binding site of an enzyme that you want r-LA binding to for the actual benefits, you have unwanted competition.  Because this is Amazon.com, let's not try to talk about chemical kinetics and binding affinity, and just say that "yes you will have competition between r-LA and s-LA" so assuming it's like equal binding affinity for each (that is a BIG assumption) if you go buy the ALA 600 mg dose: 300 mg of R-LA is there to be broken down but you have "equal" competition so it may be more like 150 mg of R-LA that is actually taken up because some of the S-LA bound to the enzymes.  Again, assuming "equal" competition is a big assumption, could be better or worse.  You should probably purchase R-LA.

Question 2

Is this the same as NA-RALA? There are other bottles on Amazon that are primarily labeled NA-RALA. This bottle says "featuring" as if it's not 100%.

Accepted Answer

In regards to "sodium intake", the following is copy & paste from the "About This Item" section:

"Note regarding sodium: The RLA in this product is stabilized with Na (sodium). However, one serving of this product contains less than 1% of the Daily Value for sodium, an insignificant contribution to dietary sources. Research suggests that sodium may impact blood pressure in some individuals only when it is consumed as sodium chloride (NaCl, table salt) and not in other forms. The sodium in this product is unlikely to affect blood pressure levels."

Question 3

Has this product been tested for purity, and is it made in the United States?

Accepted Answer

ConsumerLab.com has tested 8 or 10 Doctor's Best products, but not the Doctor's Best Alpha Lipoic Acid nor its R-Lipoic Acid. On the other hand, Consumer Lab has a comparative report on about 17 different brands of Alpha Lipoic Acid, apparently (no guarantee on this) with some side notes on R-Lipoic Acid advantages or disadvantages. I don't have the report, so can't be sure of the contents.On manufacturing location, I'd suggest contacting the home office of Doctor's Best, San Clemente California 92673. (800)777-2474 WWW.DRBVITAMINS.COM. Part of the label says Bioenhanced Na-RA is a registered trademark of GenoNova Research, Inc., and the front label mentions as a selling feature "Featuring bioenhanced Na-RALA." For further information, you should contact the company sources.And personally, I'm choosy about supplements, and Doctor's Best is one of the three supplement companies I find personally to deliver consistent products at a reasonable price.

Question 4

Is this good for neuropthy?

Accepted Answer

Yes. Works for me.Alpha Lipoic Acid contains 2 forms: R Lipoic acid &S Lipoic acid.  R is the part that is bioactive - the part that actually does something.  So 100 mg of R-LA is equivalent to 200 mg of A-LA.

ASIN	B000I4C19G
Age Range Description	Adult
Allergen Information	Gluten Free
Best Sellers Rank	#15,743 in Health ( See Top 100 in Health ) #179 in Antioxidant Supplements
Brand	Doctor's Best
Brand Name	Doctor's Best
Color	red
Container Type	Bottle
Customer Reviews	4.3 out of 5 stars 11 Reviews
Diet Type	Gluten Free
Dosage Form	100
Flavor	Unflavored
Flavour	Unflavored
Item Dimensions	5.4 x 5.4 x 9.4 centimeters
Item Form	Capsule
Item Weight	0.04 Kilograms
Item form	Capsule
Item weight	0.04 Kilograms
Manufacturer	Doctor’s Best, Inc
Manufacturer Part Number	DRB-00123
Material Features	Vegan
Material Type Free	en_AE
Model Name	Stabilized R-Lipoic Acid with BioEnhanced Na-RALA
Model Number	DRB-00123
Number of Items	1
Primary Supplement Type	Biotin
Primary supplement type	Biotin
Product Benefits	Heart Health Support
Special Ingredients	Amino Acid
Specific Uses For Product	Laboratory
Unit Count	60.0 Count
Unit count	60.0 Count

Doctor's Best Stabilized R-Lipoic Acid with BioEnhanced Na-RALA, Helps Support Glucose Metabolism and Energy Production* Non-GMO, Gluten Free, Vegan, 100 mg, 60 Count

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