Citra SolvDrain Natural Enzymatics Valencia Orange 22 Fl. Oz.

Q: Are you supposed to chase this with water? It seems like it would just sit in the trap otherwise.

Do not chase it with water. That would defeat the purpose. You want it to sit in the gunk so it can dissolve the gunk. Here is my review: https://www.amazon.com/gp/customer-reviews/RI2U3L5QR651S/ref=cm_cr_dp_d_rvw_ttl?ie=UTF8&ASIN=B0061WM2O8

Q: Can honesolv drain cleaner be used in a toilet?

The toilet drain is a lot bigger (3-4 inches?) than a sink drain (1.25-1.5 inches?), and is subject to a different kind of deposits than a sink, so I am not sure it would work unless one were to put several bottles down at once. But I am thinking that in my sink it was probably a lot of soap scum buildup, especially since the drain runs nearly horizontal for about 4-5 feet, which is going to be prone to buildup. It also depends on why the toilet is clogged. I guess I would not try it in my toilet, but would call a plumber if I can't plunge it free.