

🦿 Unlock your body's full mobility potential — because every step counts!
Doctor's Best Glucosamine Chondroitin MSM combines 1500 mg glucosamine, 1200 mg chondroitin, and 1000 mg OptiMSM per serving in a clean, non-GMO formula designed to support joint cartilage, flexibility, and overall connective tissue health. With 240 capsules per bottle, this supplement offers a 60-day supply that also promotes hair, skin, and nail vitality, making it a comprehensive choice for active professionals seeking scientifically backed joint support.
































| ASIN | B000I4DFAK |
| Best Sellers Rank | #3,548 in Health & Household ( See Top 100 in Health & Household ) #4 in Chondroitin Nutritional Supplements #5 in Chondroitin & Glucosamine Combination Nutritional Supplements #456 in Sales & Deals |
| Customer Reviews | 4.6 4.6 out of 5 stars (18,634) |
| Date First Available | March 23, 2009 |
| Department | Health and Beauty>Health and Wellness |
| Is Discontinued By Manufacturer | No |
| Item model number | DRB-00081 |
| Manufacturer | Doctor’s Best, Inc |
| Product Dimensions | 3.13 x 3.13 x 5.19 inches; 10.58 ounces |
D**E
Doctor's Best Glucosamine Chondroitin Msm with OptiMSM Capsules is a WINNER! Recommended.
I have been taking Doctor's Best Glucosamine Chondroitin MSM with OptiMSM Capsules for more than 10 years and have had positive results with this supplement. I originally took this for my knees when going up or down the stairs and would feel a sharp pain in my knees. I am a senior citizen and also a walker. After doing some research on Glucosamine Chondroitin MSM with OptiMSM Capsules products, including reading the reviews, I selected Doctor's Best. And I was most pleased to experience a significant reduction and in fact an elimination of the pain that I had been experiencing in my knees. Also, I had been having occasion pain in my hips too, and those occasional hip pains have also gone away. The pain elimination did not happen overnight, but it took several weeks to realize. And for years now, even with my daily walking, my knees do not exhibit pain! This is a product that actually works and I am so pleased to have found it. The size of the capsules is somewhat on the large size, but I am still able to swallow the capsules quite easily. And I am someone who has trouble swallowing larger size capsules, but the Doctor's Best capsules are not too large for me. Also, Doctor's Best recommends taking 2 capsules twice daily, with or without food. But my positive results have been obtained by taking 1 capsule twice daily, which saves money. I also do not have any stomach discomfort from this product. And there is no smell or flavor or taste to the capsules. The price of the product is very reasonable and is not a hindrance to its use. All in all, I have found that the Doctor's Best Glucosamine Chondroitin MSM with OptiMSM Capsules are recommended for many different reasons, and I have not found any reason to not recommend the product. Give this product a try and give it some time to work its magic. and I think you may also experience positive results.
R**O
Noticeable support for joint comfort after trying multiple options
I tried two other joint supplements over time before settling on this one, and it has worked well for me. I originally started taking it for knee discomfort, and after consistent use, I noticed a clear improvement in everyday movement and overall comfort. The effect wasn’t immediate, but it became noticeable after a few weeks of regular use, which felt realistic and sustainable. I also shared it with an older family friend (my friend’s mother), who took it for about a month. She mentioned that she felt more comfortable moving around and was pleasantly surprised by the results. Another plus is the formulation. If you compare labels, this one stands out for having a clear, straightforward ingredient list without unnecessary extras. It’s easy to understand what you’re taking, which mattered to me when choosing among many similar products. Pros: Noticeable support with consistent use Straightforward, well-known ingredients Good option after comparing multiple brands To consider: Requires regular use and some patience to notice effects Tablets are on the larger side (may matter for some people) Bottom line: A solid joint support supplement if you’re looking for something well-formulated and are willing to take it consistently. After trying several options, this is the one I’ve stuck with.
M**L
Dog Joint Supplement
I’ve been using these for a couple months as a joint supplement for my aging lab mix, and occasionally take them myself. She gets 2 capsules poured over her food every morning to help her meet the recommended dosing for her size and age, when combined with her normal food and supplements. The ratios of glucosamine/chondroitin/MSM, while not identical, are comparable to those found in brand name dog joint supplements, but at a fraction of the cost. It’s always hard to tell how well supplements really work, but considering the cost, supplement ratios, and human grade quality, I consider these good insurance against future joint problems for my dog. While a little excess glucosamine/chondroitin/MSM isn’t really harmful to dogs, but can cause stomach upset, I recommend you do some research on the dosage type and amount for your dog for the safest benefit.
V**R
Caused me dizziness from start - will try lower dosage
I am giving these a try. Two days in and I’m experiencing dizziness. I started with 4 pills right away and think I will go down to 1 pill a day to see if dizziness subsists. I feel less joint pain in my knees. I am also applying comfrey topically to my knees. So hard to say what is healing me, but I am getting better. Wish I wasn’t dizzy though.
S**Y
AMAZING PRODUCT --- Unbearable knee pain nearly gone! 8-3-2016 Update...Knee Pain is gone!!!
My doctor recommended that I go and see an Orthopedic Doctor for my worsening knee pain. He prescribed a prescription gel that I was to apply four times a day. Very messy, but I done as he told me for around 2 weeks with no improvement. I went back. They xrayed my knees and told me the joints were worn out. Bone rubbing against bone, with nothing there to cushion the shock. He gave me a shot in each knee. It helped for around a week. I couldn't get any more shots for a month, so I toughed it out. I went back in for more shots. My doctor was gone, I had a new doctor. He gave me the first shot, not too uncomfortable. Time for the second shot, in the worst of my two knees. I have never felt such pain in all my life! Tears were streaming down my cheeks, I had a tight grip of the table I was sitting on. Finally he stopped, pulled the needle out and said "I can't do this to you!" He was so sorry and didn't know what had went wrong. He then sent me for aqua therapy. This helped, while I was moving around in the 96 degree pool. My insurance would not pay for more than 2 months of treatments. It was very expensive to pay out-of-pocket. Plus since I could only go twice a week, my knees hurt just as bad the other 5 days of the week. I went back to see my doctor and he recommended something I had never heard of before. He told me that vets were having amazing success in horses with leg sprains and problems, after they started using this product. I stopped at a pharmacy and bought a bottle of Glucosamine Chondroitin MSM. I buy a lot of vitamins and supplements, most I can never tell if they are working or not. I take 3 capsules per day of these, one in the morning and two at night. I saw results within FOUR DAYS! Then I found these on Amazon. I think they work faster because they are not a solid pill, like I found locally in the pharmacy. I will never, ever run out of these again! It hurt so bad to walk before, with a constant audible crunching of bone rubbing against bone. Now that is mainly gone. These amazing pills put the cushion back, and I LOVE them! UPDATE: I have taken these for months now. My knee pain is gone! There were a few times that I went for a few days, forgetting to take them. I will not make that mistake again! Now when I fill my weekly prescription box, these are included. To me, they are more important than some of the prescriptions that I am taking!
L**H
Good overall
I’ve noticed a difference in my hair growing, you should drink plenty of water with this and take orange juice.
I**L
Reliable Joint Support With Noticeable Results
I’ve been taking Doctor’s Best Glucosamine Chondroitin MSM with OptiMSM for several months now, and I’ve noticed a significant improvement in my joint comfort and mobility. The combination of glucosamine, chondroitin, and MSM seems to work synergistically, providing relief from the stiffness I used to experience, especially in the mornings. The capsules are easy to swallow, and I appreciate that they’re non-GMO and gluten-free. One aspect I particularly like is the inclusion of OptiMSM, which is a highly purified form of MSM. It not only supports joint health but also benefits my hair and nails, which I’ve noticed have become stronger over time. The 240-count bottle offers great value, lasting me two months with the recommended dosage. Overall, this supplement has become a staple in my daily routine, and I highly recommend it to anyone seeking joint support. The taste is okay and it improves sleep quality.
S**Y
Huge Pills!
It take FOUR of these to equal one of my other brand. Four very large tablets 😑 My own fault for not reading closer. I should know better.
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