

💼 Elevate your wellness game with TMG — because your heart deserves the best!
Life Extension's TMG 500 mg delivers a potent 1000 mg dose of Trimethylglycine in 60 vegetarian liquid capsules designed to support healthy homocysteine levels and promote cardiovascular health. Gluten-free and easy to integrate into your daily routine, this supplement is a trusted choice for proactive heart wellness.









| ASIN | B00I509FZI |
| ASIN | B00I509FZI |
| Additives | Trimethylglycine (TMG) |
| Age Range Description | Child |
| Allergen Information | Gluten Free |
| Best Sellers Rank | #3,864 in Health ( See Top 100 in Health ) #75 in Amino Acid Nutritional Supplements |
| Brand | Life Extension |
| Customer Reviews | 4.4 4.4 out of 5 stars (2,022) |
| Customer reviews | 4.4 4.4 out of 5 stars (2,022) |
| Date First Available | 10 March 2014 |
| Format | Capsule |
| Is Discontinued By Manufacturer | No |
| Item model number | 01859 |
| Manufacturer | Life Extension |
| Product Dimensions | 5.08 x 5.08 x 9.53 cm; 90.72 g |
| Serving Recommendation | Two Capsules |
| Units | 60 Count |
| Weight | 0.2 Kilograms |
A**M
Not good
The pill size is so large, that it is not comfortable to swallow (with water ofc).
N**.
Effective! My 4th or 5th bottle!
A**A
Las pildoras vienen mojadas y llenas de granitos. Parace que algunas de ellas explotaron y embarraron a las demás. No lo vuelvo a comprar
P**O
The primary reason for adding TMG when using NMN or NR is because they increase intracellular NAD⁺ levels which accelerates the activity of methyltransferase enzymes. This can create a significant demand for methyl groups and temporarily elevate homocysteine if methyl donors are insufficient. TMG serves as a methyl donor directly converting homocysteine back to methionine via the betaine-homocysteine methyltransferase pathway. Two capsules with breakfast provide exactly the 1–1.5 g range frequently cited in longevity-focused protocols. For anyone incorporating NMN, NR, or high-dose niacin into a longevity regimen, I consider TMG essential for maintaining methylation balance and minimizing potential homocysteine elevation. This particular TMG offering from Life Extension delivers reliable purity, potency, and value.
U**H
Me encanta, buena relación precio/ calidad
J**L
Appears to be good clean quality and transparent capsules where you can see the product. I took a methylation test a while back and discovered partial COMT varient issues. In taking these I notice a sustained energy throughout the day. Not sure if it's just a coincidence at this point but I will be continuing with this brand's tmg.
Trustpilot
3 days ago
1 day ago