SAM-e 200mg (60 Tablets) (1-Pack) Premium Ingredient from Italy.

I have to give this product 5 stars and I almost never review my purchases. I did the research to identify the most potent supplement and it came back loud and clear that BestVite was one of just a couple available on Amazon. You will get your money's worth with this product, it's highly effective even at a low dose and doesn't compare to other Sam-e supplements I've purchased.

I am using Sam-e for over 10 years and I found this brand lately and price and quality is extremely good !!

After the birth of our last baby, I was suffering from some mild depression. I had a bad experience years ago with anti-depressants and was very reluctant to take them again. I have been taking this for two months and noticed a significant improvement in my mood and outlook after the first week or two. I take one on an empty stomach when I get up in the morning, and it doesn't cause any nausea or upset stomach. I also deal with some anxiety, so I take StressRx daily as well, and this combination has been working very well for me.

I’ve been taking SAMe for years with great success. It’s excellent for depression. Decided to try this brand because it was cheaper. I’ve gone through two bottles in a month and I don’t feel like I’ve taken anything. A total waste of money. Back to my other brand .

I have been taking SAMe since March to treat fibromyalgia. The Bestvite product is excellent. It has given me more energy, and when I am experiencing pain, SAMe will diminish the pain. I take 600 mg. per day. I do keep it refrigerated as instructed on the label. When I am traveling I take SAMe tablets in a blister pack --- Doctor's Best product. The Bestvite SAMe is effective, but because SAMe is not stable, I cannot take it with me when traveling.

Recommended by my veterinarian as a supplemental treatment for life-threatening canine liver issues. The important word there is supplemental; please don't try to treat serious medical problems based on anecdotal evidence of a single drug working as intended. That said, these did work along with prescription medications to treat a severe liver problem in one of my dogs. Blood work slowly returned to normal over a 6-month period and she is now fully recovered. As we tapered off the prescriptions, continued to give SAMe for the last two months (and will continue for a couple more). The "enteric" coating does appear to help with a sensitive stomach - if your dog tends to regurgitate medicines or other things they need to keep down.

I have used SAMe for a number of years. Although I take 400mgs most days I like to break it up into two doses which can be more evenly used through the day, rather than one tablet. But that is me. However, my body tells me that this is a good quality. It seems the cheaper ones I can forget to take. The higher quality SAMe reminds me, it seems, to take it. This stuff reminds me to take it.

The ingredients do not list mannitol as an ingredient, but this supplement clearly contains mannitol. I've taken sam-e with mannitol before, and I cannot tolerate it--severe stomach cramps, which is not unusual for many people who are sensitive to this particular sugar alcohol. Beware if you have a sensitive stomach. Don't buy thinking that it is mannitol free. It's not.